模型信息
中文名称:MERS-CoV MERS-15滴鼻感染288-330+/-小鼠模型
英文名称:MERS-CoV MERS-15 intranasally infection 288-330+/- mouse model
类型:MERS-CoV感染动物模型
分级:NA
用途:用于MERS-CoV感染研究。
研制单位:北卡罗来纳大学教堂山分校@@http://www.unc.edu/
保存单位:北卡罗来纳大学教堂山分校@@http://www.unc.edu/
研究背景
暂无介绍
制备方法
Mouse adapted MERS-CoV causes fatal disease in 288-330+/+ mice. Mice were inoculated intranasally with 5×106 PFU.Data reflect percent of surviving mice. Mouse weights were measured daily through day 6 post-infection for 288-330+/+ + MERS-15 (n = 16); 288-330+/− + MERS-15 (n = 10), 288-330+/+ + MERS-0 (n = 10), and C57Bl/6J wt + MERS-15 (n = 7).
评价验证
暂无介绍
生物安全性
暂无介绍
讨论与结论
体重下降,病毒在肺中复制
了解中析
实验室仪器
合作客户
